Metòd komen pwoteksyon amine
1. Cbz
Benzyloxycarbonyl (Cbz) Pwoteje Amino
Depwoteksyon N-benzyloxycarbonyl (Cbz)
Souvan itilize réactifs - CbzCl
2. Alloc
Allyloxycarbonyl (Alloc) gwoup amine pwoteje
3. Trifluoroacetyl
Trifluoroacetyl pwoteje gwoup amine
4. Benzyls
p-methoxybenzyl (PMB) pwoteje gwoup amine
2,4-dimethoxybenzyl pwoteje gwoup amine
Benzyl pwoteje amino
Depwoteksyon nan gwoup amino benzyl-pwoteje
N-Bn debenzylation pa metòd chloroformate
5. Pht (phthaloyl)
Phthaloyl (Pht) gwoup amine pwoteje
Depwoteksyon nan gwoup amine phthaloyl-pwoteje
6. Benzenesulfonyl
Nitrobenzenesulfonyl pwoteje gwoup amine
p-toluenesulfonyl (Tos) pwoteksyon amine
7. Trt
Trityl pwoteje amino
Depwoteksyon nan trityl-pwoteje gwoup amine
8. Bok
Tert-butoxicarbonyl pwoteje gwoup amine
Depwoteksyon nan N-tèt-butoxicarbonyl
Oxalyl klori De-Boc
9. Fmoc
Wat methoxycarbonyl pwoteje gwoup amine
Reyaktif souvan itilize - Fmoc-Cl
10. SEM
SEM pwoteje amino
11. Lòt moun
Acetamid pwoteje gwoup amine
Reyaksyon sentèz pirrol Clauson-Kaas (reyaksyon sa a ka itilize kòm yon metòd pou pwoteje gwoup amine, ka ranplase doub pwoteksyon Boc, epi li pi estab)
Souvan itilize reyaktif - benzyl (chloromethyl) etè
Reyaktif souvan itilize - (kloromethyl) etè methyl [MOMCl]
Pwoteksyon Carbamate
Tan pòs: Sep-07-2023